Scientists say they can cut HIV out of cells using Crispr gene-editing technology

Wednesday, March 20, 2024 – Scientists say they have successfully eliminated HIV from infected cells, using Nobel Prize-winning Crispr gene-editing technology, the BBC reports.

The technology works like scissors, but at the molecular level, to cut DNA so that “bad” bits can be removed or inactivated.

The hope is to ultimately be able to rid the body entirely of the virus, although much more work is needed to check it would be safe and effective.

Existing HIV medicines can stop the virus but not eliminate it.

The University of Amsterdam team, presenting a synopsis of their early findings at a medical conference this week, stressed that their work remains merely “proof of concept” and will not become a cure for HIV any time soon.

And Dr James Dixon, stem-cell and gene-therapy technologies associate professor at the University of Nottingham, agrees, saying the full findings still require scrutiny.

“Much more work will be needed to demonstrate results in these cell assays can happen in an entire body for a future therapy,” he said.